ARF1 antibody (AA 2-181) (FITC)

Catalog No. ABIN7143444

The Rabbit Polyclonal anti-ARF1 antibody has been validated for . It is suitable to detect ARF1 in samples from Human.

Quick Overview for ARF1 antibody (AA 2-181) (FITC) (ABIN7143444)

Target: ARF1 (ADP-Ribosylation Factor 1 (ARF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARF1 antibody is conjugated to FITC

Application: Please inquire

Product Details anti-ARF1 Antibody (FITC)

Binding Specificity: AA 2-181

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human ADP-ribosylation factor 1 protein (2-181AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ARF1

Target: ARF1 (ADP-Ribosylation Factor 1 (ARF1))

Alternative Name: ARF1

Background:

Background: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity, the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).

Aliases: ADP Ribosylation Factor 1 antibody, ADP-ribosylation factor 1 antibody, ARF 1 antibody, ARF1 antibody, ARF1_HUMAN antibody

UniProt: P84077

Pathways: Transition Metal Ion Homeostasis, Inositol Metabolic Process