ARFGAP1 antibody (AA 1-220)

Catalog No. ABIN7143460

This anti-ARFGAP1 antibody is a Rabbit Polyclonal antibody detecting ARFGAP1 in WB, ELISA and IHC. Suitable for Human.

Quick Overview for ARFGAP1 antibody (AA 1-220) (ABIN7143460)

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARFGAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ARFGAP1 Antibody

Binding Specificity: AA 1-220

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human ADP-ribosylation factor GTPase-activating protein 1 protein (1-220AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ARFGAP1

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Alternative Name: ARFGAP1

Background:

Background: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle\\\'s fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine .

Aliases: ADP ribosylation factor 1 GTPase activating protein antibody, ADP ribosylation factor GTPase activating protein 1 antibody, ADP-ribosylation factor 1 GTPase-activating protein antibody, ADP-ribosylation factor GTPase-activating protein 1 antibody, ARF GAP 1 antibody, ARF1 directed GTPase activating protein antibody, ARF1 GAP antibody, ARF1-directed GTPase-activating protein antibody, ARF1GAP antibody, ARFG1_HUMAN antibody, Arfgap1 antibody, GAP protein antibody, HRIHFB2281 antibody

UniProt: Q8N6T3

Pathways: p53 Signaling, ER-Nucleus Signaling, Unfolded Protein Response