AIMP2 antibody (AA 141-320)

Catalog No. ABIN7143999

Product Details anti-AIMP2 Antibody

Target: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Binding Specificity: AA 141-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIMP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein (141-320AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AIMP2

Target: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Alternative Name: AIMP2 (AIMP2 Products)

Synonyms: jtv1 antibody, MGC53242 antibody, pro0992 antibody, JTV1 antibody, JTV-1 antibody, P38 antibody, AA407136 antibody, AA407225 antibody, Aimp2(p38) antibody, Jtv1 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 antibody, aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antibody, aimp2.L antibody, aimp2 antibody, AIMP2 antibody, Aimp2 antibody

Background:

Background: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Aliases: Aimp2 antibody, AIMP2_HUMAN antibody, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 antibody, Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antibody, ARS interacting multi functional protein 2 antibody, JTV 1 antibody, JTV 1 protein antibody, JTV1 antibody, JTV1 gene antibody, Multisynthase complex auxiliary component p38 antibody, Multisynthetase complex auxiliary component p38 antibody, P38 antibody, PRO0992 antibody, Protein JTV 1 antibody, Protein JTV-1 antibody, tRNA SYNTHETASE COFACTOR p38 antibody

UniProt: Q13155