BSND antibody (AA 54-320)
Quick Overview for BSND antibody (AA 54-320) (ABIN7145262)
Target
See all BSND AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 54-320
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Purpose
- BSND Antibody
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Barttin protein (54-320AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BSND (Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND))
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Alternative Name
- BSND
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Background
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Background: Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.
Aliases: BART antibody, Bartter syndrome infantile with sensorineural deafness antibody, Bartter syndrome, infantile, with sensorineural deafness (Barttin) antibody, Barttin antibody, Bsnd antibody, BSND_HUMAN antibody, deafness, autosomal recessive 73 antibody, DFNB 73 antibody, DFNB73 antibody
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UniProt
- Q8WZ55
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Pathways
- Sensory Perception of Sound
Target
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