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Caspase 1 antibody (AA 120-269) (Biotin)

The Rabbit Polyclonal anti-Caspase 1 antibody has been validated for ELISA. It is suitable to detect Caspase 1 in samples from Human.
Catalog No. ABIN7146927

Quick Overview for Caspase 1 antibody (AA 120-269) (Biotin) (ABIN7146927)

Target

See all Caspase 1 (CASP1) Antibodies
Caspase 1 (CASP1)

Reactivity

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  • 39
  • 35
  • 7
  • 2
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  • 1
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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Caspase 1 antibody is conjugated to Biotin

Application

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ELISA
  • Binding Specificity

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    AA 120-269

    Cross-Reactivity

    Human

    Purification

    >95%, Protein G purified

    Immunogen

    Recombinant Human Caspase-1 protein (120-269AA)

    Isotype

    IgG
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    Caspase 1 (CASP1)

    Alternative Name

    CASP1

    Background

    Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

    Aliases: CASP-1 antibody, CASP1 antibody, CASP1_HUMAN antibody, Caspase 1 antibody, Caspase-1 subunit p10 antibody, ICE antibody, IL-1 beta-converting enzyme antibody, IL-1BC antibody, IL1 beta converting enzyme antibody, IL1B convertase antibody, Interleukin 1 beta convertase antibody, Interleukin 1B converting enzyme antibody, Interleukin-1 beta convertase antibody, Interleukin-1 beta-converting enzyme antibody, p45 antibody

    UniProt

    P29466

    Pathways

    Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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