Caspase 1 antibody (AA 120-269) (Biotin)
Quick Overview for Caspase 1 antibody (AA 120-269) (Biotin) (ABIN7146927)
Target
See all Caspase 1 (CASP1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 120-269
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Caspase-1 protein (120-269AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Caspase 1 (CASP1)
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Alternative Name
- CASP1
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Background
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Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Aliases: CASP-1 antibody, CASP1 antibody, CASP1_HUMAN antibody, Caspase 1 antibody, Caspase-1 subunit p10 antibody, ICE antibody, IL-1 beta-converting enzyme antibody, IL-1BC antibody, IL1 beta converting enzyme antibody, IL1B convertase antibody, Interleukin 1 beta convertase antibody, Interleukin 1B converting enzyme antibody, Interleukin-1 beta convertase antibody, Interleukin-1 beta-converting enzyme antibody, p45 antibody
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UniProt
- P29466
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Pathways
- Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
Target
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