Caspase 1 antibody (AA 120-269) (HRP)

Catalog No. ABIN7146931

This anti-Caspase 1 antibody is a Rabbit Polyclonal antibody detecting Caspase 1 in ELISA. Suitable for Human.

Quick Overview for Caspase 1 antibody (AA 120-269) (HRP) (ABIN7146931)

Target: Caspase 1 (CASP1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 1 antibody is conjugated to HRP

Application: ELISA

Product Details anti-Caspase 1 Antibody (HRP)

Binding Specificity: AA 120-269

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Caspase-1 protein (120-269AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Caspase 1

Target: Caspase 1 (CASP1)

Alternative Name: CASP1

Background:

Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Aliases: CASP-1 antibody, CASP1 antibody, CASP1_HUMAN antibody, Caspase 1 antibody, Caspase-1 subunit p10 antibody, ICE antibody, IL-1 beta-converting enzyme antibody, IL-1BC antibody, IL1 beta converting enzyme antibody, IL1B convertase antibody, Interleukin 1 beta convertase antibody, Interleukin 1B converting enzyme antibody, Interleukin-1 beta convertase antibody, Interleukin-1 beta-converting enzyme antibody, p45 antibody

UniProt: P29466

Pathways: Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome