CDC42 antibody (AA 2-188)

Catalog No. ABIN7344422

Product Details anti-CDC42 Antibody

Target: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Binding Specificity: AA 2-188

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC42 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cell division control protein 42 homolog protein (2-188AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CDC42

Target: CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))

Alternative Name: CDC42 (CDC42 Products)

Background:

Background: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration.

Aliases: CDC42 antibody, CDC42_HUMAN antibody, CDC42Hs antibody, Cell division control protein 42 homolog antibody, Cell division cycle 42 (GTP binding protein 25 kDa) antibody, Cell division cycle 42 antibody, dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)) antibody, dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)) antibody, G25K antibody, G25K GTP-binding protein antibody, Growth regulating protein antibody, GTP binding protein 25 kDa antibody, Small GTP binding protein CDC42 antibody, TKS antibody

UniProt: P60953

Pathways: MAPK Signaling, Microtubule Dynamics, RTK Signaling, WNT Signaling, TCR Signaling, EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Signaling Events mediated by VEGFR1 and VEGFR2, EGFR Downregulation, VEGF Signaling