CDC23 antibody (AA 62-142) (HRP)

Catalog No. ABIN7147306

Product Details anti-CDC23 Antibody (HRP)

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Binding Specificity: AA 62-142

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC23 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cell division cycle protein 23 homolog protein (62-142AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CDC23

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Alternative Name: CDC23 (CDC23 Products)

Synonyms: CDC23 antibody, anaphase-promoting complex subunit 8 antibody, zgc:56013 antibody, 6030435O18 antibody, D18Ertd243e antibody, ANAPC8 antibody, APC8 antibody, CUT23 antibody, cell division cycle 23 antibody, cell division cycle protein 23 homolog antibody, anaphase-promoting complex subunit 8 antibody, CDC23 (cell division cycle 23, yeast, homolog) antibody, cell division cycle 23 S homeolog antibody, CDC23 cell division cycle 23 antibody, CDC23 antibody, LOC100162672 antibody, LOC100380698 antibody, APC8 antibody, cdc23 antibody, cdc23.S antibody, Cdc23 antibody

Background:

Background: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of \'Lys-11\'-linked polyubiquitin chains and, to a lower extent, the formation of \'Lys-48\'- and \'Lys-63\'-linked polyubiquitin chains.

Aliases: ANAPC8 antibody, Anaphase promoting complex subunit 8 antibody, Anaphase-promoting complex subunit 8 antibody, Apc 8 antibody, APC8 antibody, Cdc 23 antibody, CDC23 antibody, CDC23_HUMAN antibody, cell division cycle 23 antibody, Cell division cycle 23 homolog antibody, Cell division cycle protein 23 antibody, Cell division cycle protein 23 homolog antibody, Cut23 antibody, Cyclosome subunit 8 antibody

UniProt: Q9UJX2

Pathways: Protein targeting to Nucleus