CDYL antibody (AA 8-260) (FITC)
Quick Overview for CDYL antibody (AA 8-260) (FITC) (ABIN7147712)
Target
See all CDYL AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 8-260
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Chromodomain Y-like protein (8-260AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CDYL (Chromodomain Protein, Y-Like (CDYL))
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Alternative Name
- CDYL
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Background
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Background: Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2), acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4.
Aliases: CDY-like antibody, CDY-like autosomal antibody, Cdyl antibody, CDYL: chromodomain protein Y-like antibody, CDYL1 antibody, CDYL1_HUMAN antibody, chromodomain protein Y chromosome-like 6 antibody, Chromodomain protein Y like antibody, Chromodomain Y-like protein antibody, DKFZP586C1622 antibody, MGC131936 antibody, OTTHUMP00000015984 antibody, OTTHUMP00000211185 antibody, OTTHUMP00000211186 antibody, OTTHUMP00000211189 antibody, testis-specific chromodomain Y-like protein antibody, Weakly similar to enoyl-CoA hydratase [H.sapiens] antibody
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UniProt
- Q9Y232
Target
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