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COPS7A antibody (AA 2-275) (Biotin)

COPS7A Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7148500
  • Target See all COPS7A Antibodies
    COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
    Binding Specificity
    • 10
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    AA 2-275
    Reactivity
    • 45
    • 22
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 44
    • 1
    Rabbit
    Clonality
    • 45
    Polyclonal
    Conjugate
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COPS7A antibody is conjugated to Biotin
    Application
    • 40
    • 21
    • 19
    • 5
    • 2
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human COP9 signalosome complex subunit 7a protein (2-275AA)
    Isotype
    IgG
    Top Product
    Discover our top product COPS7A Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
    Alternative Name
    COPS7A (COPS7A Products)
    Synonyms
    D6Ertd35e antibody, CSN7A antibody, COP9 signalosome subunit 7A antibody, COPS7A antibody, Cops7a antibody
    Background

    Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

    Aliases: COP9 complex subunit 7a antibody, COP9 constitutive photomorphogenic homolog subunit 7A antibody, COP9 signalosome complex subunit 7a antibody, COP9 signalosome subunit 7A antibody, COPS7A antibody, CSN7A antibody, CSN7A_HUMAN antibody, Dermal papilla derived protein 10 antibody, Dermal papilla-derived protein 10 antibody, DERP10 antibody, JAB1 containing signalosome subunit 7a antibody, JAB1-containing signalosome subunit 7a antibody, SGN7a antibody, Signalosome subunit 7a antibody

    UniProt
    Q9UBW8
    Pathways
    Cell Division Cycle
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