CRTC3 antibody (AA 373-480) (Biotin)

Catalog No. ABIN7148684

This Rabbit Polyclonal antibody specifically detects CRTC3 in ELISA. It exhibits reactivity toward Human.

Quick Overview for CRTC3 antibody (AA 373-480) (Biotin) (ABIN7148684)

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTC3 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-CRTC3 Antibody (Biotin)

Binding Specificity: AA 373-480

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human CREB-regulated transcription coactivator 3 protein (373-480AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Alternative Name: CRTC3

Background:

Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 \'Ser-133\' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

Aliases: CREB regulated transcription coactivator 3 antibody, CREB-regulated transcription coactivator 3 antibody, CRTC 3 antibody, CRTC3 antibody, CRTC3_HUMAN antibody, FLJ21868 antibody, TORC 3 antibody, TORC-3 antibody, TORC3 antibody, Transducer of CREB protein 3 antibody, Transducer of regulated cAMP response element binding protein (CREB) 3 antibody, Transducer of regulated cAMP response element binding protein 3 antibody, Transducer of regulated cAMP response element-binding protein 3 antibody, Transducer of regulated CREB protein 3 antibody

UniProt: Q6UUV7

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection