Nitrilase 1 antibody (AA 1-243)

Catalog No. ABIN7149534

The Rabbit Polyclonal anti-Nitrilase 1 antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect Nitrilase 1 in samples from Human.

Quick Overview for Nitrilase 1 antibody (AA 1-243) (ABIN7149534)

Target: Nitrilase 1 (NIT1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nitrilase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Nitrilase 1 Antibody

Binding Specificity: AA 1-243

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Deaminated glutathione amidase protein (1-243AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000, IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Nitrilase 1

Target: Nitrilase 1 (NIT1)

Alternative Name: NIT1

Background:

Background: Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells, this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells.

Aliases: MGC57670 antibody, NIT1 antibody, NIT1_HUMAN antibody, Nitrilase 1 antibody, Nitrilase homolog 1 antibody

UniProt: Q86X76