ERCC1 antibody (AA 1-323) (HRP)

Catalog No. ABIN7150171

This anti-ERCC1 antibody is a Rabbit Polyclonal antibody detecting ERCC1 in ELISA. Suitable for Human.

Quick Overview for ERCC1 antibody (AA 1-323) (HRP) (ABIN7150171)

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC1 antibody is conjugated to HRP

Application: ELISA

Product Details anti-ERCC1 Antibody (HRP)

Binding Specificity: AA 1-323

Purpose: ERCC1 Antibody, HRP conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human DNA excision repair protein ERCC-1 protein (1-323AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ERCC1

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Alternative Name: ERCC1

Background:

Background: Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5\'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.

Aliases: COFS 4 antibody, COFS4 antibody, DNA excision repair protein ERCC 1 antibody, DNA excision repair protein ERCC-1 antibody, DNA excision repair protein ERCC1 antibody, ERCC 1 antibody, ERCC1 antibody, ERCC1_HUMAN antibody, Excision repair cross complementation group 1 antibody, Excision repair cross complementing 1 antibody, Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 antibody, Excision repair protein antibody, RAD 10 antibody, RAD10 antibody, UV 20 antibody, UV20 antibody

UniProt: P07992

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response