POLB antibody (AA 1-300) (HRP)

Catalog No. ABIN7150226

This Rabbit Polyclonal antibody specifically detects POLB in ELISA. It exhibits reactivity toward Human.

Quick Overview for POLB antibody (AA 1-300) (HRP) (ABIN7150226)

Target: POLB (Polymerase (DNA Directed), beta (POLB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLB antibody is conjugated to HRP

Application: ELISA

Product Details anti-POLB Antibody (HRP)

Binding Specificity: AA 1-300

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DNA polymerase beta protein (1-300AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for POLB

Target: POLB (Polymerase (DNA Directed), beta (POLB))

Alternative Name: POLB

Background:

Background: Repair polymerase that plays a key role in base-excision repair. Has 5\'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5\' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3\' end of the arising single-nucleotide gap. Conducts \'gap-filling\' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

Aliases: DNA directed DNA polymerase beta antibody, DNA pol beta antibody, DNA polymerase beta antibody, DNA polymerase beta subunit antibody, DPOLB_HUMAN antibody, MGC125976 antibody, Pol B antibody, Pol beta antibody, POLB antibody, Polymerase (DNA directed) beta antibody

UniProt: P06746

Pathways: DNA Damage Repair