MCM7 antibody (AA 360-719)

Catalog No. ABIN7150341

The Rabbit Polyclonal anti-MCM7 antibody has been validated for IHC and ELISA. It is suitable to detect MCM7 in samples from Human.

Quick Overview for MCM7 antibody (AA 360-719) (ABIN7150341)

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM7 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-MCM7 Antibody

Binding Specificity: AA 360-719

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human DNA replication licensing factor MCM7 protein (360-719AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MCM7

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Alternative Name: MCM7

Background:

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for \\\'once per cell cycle\\\' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.

Aliases: CDABP0042 antibody, CDC 47 antibody, CDC47 antibody, CDC47 homolog antibody, Cdc47, S. cerevisiae, homolog of antibody, DNA replication licensing factor MCM7 antibody, Homolog of S. cerevisiae Cdc47 antibody, MCM 2 antibody, MCM 7 antibody, MCM2 antibody, MCM2, formerly antibody, Mcm7 antibody, MCM7 minichromosome maintenance deficient 7 antibody, MCM7_HUMAN antibody, Minichromosome Maintainence 7 antibody, Minichromosome maintainence, S. cerevisiae, homolog of antibody, Minichromosome maintenance complex component 7 antibody, Minichromosome maintenance deficient 7 antibody, Minichromosome maintenance protein 7 antibody, P1.1 MCM3 antibody, P1.1-MCM3 antibody, P1CDC47 antibody, P85MCM antibody, PNAS 146 antibody, PNAS146 antibody, PPP1R104 antibody, Protein phosphatase 1, regulatory subunit 104 antibody

UniProt: P33993

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA