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NDEL1 antibody (pThr219) (HRP)

NDEL1 Reactivity: Rat ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal HRP
Catalog No. ABIN710840
  • Target See all NDEL1 Antibodies
    NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))
    Binding Specificity
    • 21
    • 15
    • 15
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    pThr219
    Reactivity
    • 63
    • 53
    • 46
    • 2
    • 1
    Rat
    Host
    • 86
    • 3
    • 1
    Rabbit
    Clonality
    • 78
    • 12
    Polyclonal
    Conjugate
    • 21
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    This NDEL1 antibody is conjugated to HRP
    Application
    • 52
    • 52
    • 45
    • 19
    • 13
    • 11
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human NDEL1 around the phosphorylation site of Thr219
    Isotype
    IgG
    Top Product
    Discover our top product NDEL1 Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))
    Alternative Name
    NDEL1 (NDEL1 Products)
    Synonyms
    EOPA antibody, MITAP1 antibody, NDE1L1 antibody, NDE2 antibody, NUDEL antibody, NUDE2 antibody, Nudel antibody, 2600006O07Rik antibody, mNudel antibody, wu:fi23c04 antibody, wu:fi23e06 antibody, eopa antibody, mitap1 antibody, ndel1 antibody, ndel1-a antibody, ndel1-b antibody, nudel antibody, nudE neurodevelopment protein 1 like 1 antibody, nudE neurodevelopment protein 1-like 1 antibody, nudE neurodevelopment protein 1-like 1b antibody, nudE neurodevelopment protein 1 like 1 L homeolog antibody, NDEL1 antibody, Ndel1 antibody, ndel1b antibody, ndel1.L antibody
    Background

    Synonyms: NDEL1phospho T219, Nudelphospho T219, A. nidulans, DKFZp451M0318, ENDOOLIGOPEPTIDASE A, EOPA, MITAP 1, MITAP1, Mitosin associated protein 1, Mitosin associated protein MITAP1, Mitosin-associated protein 1, Ndel 1, Ndel1, NDEL1_HUMAN, Nuclear distribution gene E like homolog 1, Nuclear distribution protein nudE like 1, Nuclear distribution protein nudE-like 1, NUDE like protein, NudE nuclear distribution gene E homolog like 1 A. nidulans, NudE nuclear distribution gene E homolog like 1, NUDEL, Protein Nudel.

    Background: Nudel is important for normal cortical development. It is invovled in microtubule organization, nuclear translocation, and neuronal positioning in concert with various other factors (including Lis1, Pafah1b1, Pahfah1b2, dynein, dynorphin A and cdk5). Western blot analysis of mouse tissues shows abundant expression of Nudel in brain and testis, and much lower expression in heart, liver, kidney, and skeletal muscle. In fractionated rat brain, Nudel and Lis1 are both found in fractions enriched for postsynaptic density proteins. Immunostaining of embryonic day 18 mouse brain sections revealed staining of migrating neurons and thalamocortical axons of the intermediate zone of the developing cerebral cortex, as well as several other developing brain regions. The deduced protein contains 345 amino acids and has a calculated molecular mass of 38.4 kDa. It has a coiled coil motif (residues 19 to 201), followed by several potential phosphorylation sites for casein kinase II, protein kinase C or CDK5. Nudel shares about 50 % identity with mouse and human NUDE proteins.

    Gene ID
    81565
    Pathways
    Regulation of Cell Size
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