ENPP1 antibody (AA 1-75)

Catalog No. ABIN7151385

Product Details anti-ENPP1 Antibody

Target: ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

Binding Specificity: AA 1-75

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 protein (1-75AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ENPP1

Target: ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

Alternative Name: ENPP1 (ENPP1 Products)

Synonyms: ENPP1 antibody, si:ch211-142e24.2 antibody, zgc:136238 antibody, ARHR2 antibody, M6S1 antibody, NPP1 antibody, NPPS antibody, PC-1 antibody, PCA1 antibody, PDNP1 antibody, 4833416E15Rik antibody, AI428932 antibody, C76301 antibody, CD203c antibody, E-NPP1 antibody, Ly-41 antibody, Npps antibody, Pca antibody, Pca-1 antibody, Pdnp1 antibody, ttw antibody, twy antibody, Pc1 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 1 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 1 L homeolog antibody, ENPP1 antibody, enpp1 antibody, enpp1.L antibody, Enpp1 antibody

Background:

Background: By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5\' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3\',5\'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.

Aliases: Alkaline phosphodiesterase 1 antibody, ARHR2 antibody, COLED antibody, E-NPP 1 antibody, Ectonucleotide pyrophosphatase/phosphodiesterase 1 antibody, Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 antibody, ENPP1 antibody, ENPP1_HUMAN antibody, Ly 41 antigen antibody, M6S1 antibody, Membrane component chromosome 6 surface marker 1 antibody, NPP1 antibody, NPPase antibody, NPPS antibody, Nucleotide pyrophosphatase antibody, PC 1 antibody, PC-1 antibody, PCA1 antibody, PDNP1 antibody, Phosphodiesterase I/nucleotide pyrophosphatase 1 antibody, Plasma cell membrane glycoprotein 1 antibody, Plasma-cell membrane glycoprotein PC-1 antibody

UniProt: P22413

Pathways: Regulation of Carbohydrate Metabolic Process