ENPP1 antibody (AA 1-75) (HRP)

Catalog No. ABIN7151388

The Rabbit Polyclonal anti-ENPP1 antibody has been validated for ELISA. It is suitable to detect ENPP1 in samples from Human.

Quick Overview for ENPP1 antibody (AA 1-75) (HRP) (ABIN7151388)

Target: ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP1 antibody is conjugated to HRP

Application: ELISA

Product Details anti-ENPP1 Antibody (HRP)

Binding Specificity: AA 1-75

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 protein (1-75AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ENPP1

Target: ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

Alternative Name: ENPP1

Background:

Background: By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5\' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3\',5\'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.

Aliases: Alkaline phosphodiesterase 1 antibody, ARHR2 antibody, COLED antibody, E-NPP 1 antibody, Ectonucleotide pyrophosphatase/phosphodiesterase 1 antibody, Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 antibody, ENPP1 antibody, ENPP1_HUMAN antibody, Ly 41 antigen antibody, M6S1 antibody, Membrane component chromosome 6 surface marker 1 antibody, NPP1 antibody, NPPase antibody, NPPS antibody, Nucleotide pyrophosphatase antibody, PC 1 antibody, PC-1 antibody, PCA1 antibody, PDNP1 antibody, Phosphodiesterase I/nucleotide pyrophosphatase 1 antibody, Plasma cell membrane glycoprotein 1 antibody, Plasma-cell membrane glycoprotein PC-1 antibody

UniProt: P22413

Pathways: Regulation of Carbohydrate Metabolic Process