Endoglin antibody (AA 32-259) (HRP)
Quick Overview for Endoglin antibody (AA 32-259) (HRP) (ABIN7151625)
Target
See all Endoglin (ENG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 32-259
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Endoglin protein (32-259AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Endoglin (ENG)
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Alternative Name
- ENG
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Background
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Background: Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
Aliases: AI528660 antibody, AI662476 antibody, CD 105 antibody, CD105 antibody, CD105 antigen antibody, EGLN_HUMAN antibody, END antibody, Endoglin antibody, Eng antibody, FLJ41744 antibody, HHT1 antibody, ORW antibody, ORW1 antibody, Osler Rendu Weber syndrome 1 antibody, RP11 228B15.2 antibody, S endoglin antibody, S-endoglin antibody, SN6 antibody
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UniProt
- P17813
Target
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