SLC1A3 antibody (AA 146-236)

Catalog No. ABIN7152226

This anti-SLC1A3 antibody is a Rabbit Polyclonal antibody detecting SLC1A3 in ELISA, IHC and IF. Suitable for Human.

Quick Overview for SLC1A3 antibody (AA 146-236) (ABIN7152226)

Target: SLC1A3 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC1A3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SLC1A3 Antibody

Binding Specificity: AA 146-236

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Excitatory amino acid transporter 1 protein (146-236AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SLC1A3

Target: SLC1A3 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3))

Alternative Name: SLC1A3

Background:

Background: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7521911, PubMed:8123008, PubMed:20477940, PubMed:26690923, PubMed:28032905, PubMed:28424515). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:20477940). Mediates Cl(-) flux that is not coupled to amino acid transport, this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:20477940). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).

Aliases: EA6 antibody, EAA1_HUMAN antibody, EAAT1 antibody, Excitatory amino acid transporter 1 antibody, FLJ25094 antibody, GLAST antibody, GLAST-1 antibody, GLAST1 antibody, Glial high affinity glutamate transporter antibody, glutamate/aspartate transporter, high affinity, sodium-dependent antibody, High affinity neuronal glutamate transporter antibody, Slc1a3 antibody, Sodium dependent glutamate/aspartate transporter antibody, Sodium-dependent glutamate/aspartate transporter 1 antibody, Solute carrier family 1 (glial high affinity glutamate transporter) member 3 antibody, Solute carrier family 1 member 3 antibody

UniProt: P43003

Pathways: Sensory Perception of Sound, Synaptic Membrane, Dicarboxylic Acid Transport