FANCM antibody (AA 390-660)
Quick Overview for FANCM antibody (AA 390-660) (ABIN7152565)
Target
See all FANCM AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 390-660
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Fanconi anemia group M protein (390-660AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FANCM (Fanconi Anemia Complementation Group M (FANCM))
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Alternative Name
- FANCM
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Background
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Background: ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.
Aliases: FANCM antibody, KIAA1596Fanconi anemia group M protein antibody, Protein FACM antibody, EC 3.6.4.13 antibody, ATP-dependent RNA helicase FANCM antibody, Fanconi anemia-associated polypeptide of 250 kDa antibody, FAAP250 antibody, Protein Hef ortholog antibody
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UniProt
- Q8IYD8
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Pathways
- DNA Damage Repair
Target
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