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Glucagon Receptor antibody (AA 26-136)

GCGR Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7153869
  • Target See all Glucagon Receptor (GCGR) Antibodies
    Glucagon Receptor (GCGR)
    Binding Specificity
    • 16
    • 9
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-136
    Reactivity
    • 55
    • 26
    • 25
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Human
    Host
    • 53
    • 1
    • 1
    Rabbit
    Clonality
    • 54
    • 1
    Polyclonal
    Conjugate
    • 21
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glucagon Receptor antibody is un-conjugated
    Application
    • 40
    • 23
    • 18
    • 13
    • 13
    • 12
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Glucagon receptor protein (26-136AA)
    Isotype
    IgG
    Top Product
    Discover our top product GCGR Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Glucagon Receptor (GCGR)
    Alternative Name
    GCGR (GCGR Products)
    Synonyms
    GCGR antibody, GGR antibody, GR antibody, glucagon receptor antibody, GCGR antibody, Gcgr antibody
    Background

    Background: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.

    Aliases: Gcgr antibody, GGR antibody, GL R antibody, GL-R antibody, GLR antibody, GLR_HUMAN antibody, Glucagon receptor antibody, Glucagon receptor precursor antibody, MGC138246 antibody

    UniProt
    P47871
    Pathways
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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