GRIK1 antibody (AA 675-834)

Catalog No. ABIN7153969

This anti-GRIK1 antibody is a Rabbit Polyclonal antibody detecting GRIK1 in ELISA, IHC and IF. Suitable for Human.

Quick Overview for GRIK1 antibody (AA 675-834) (ABIN7153969)

Target: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIK1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GRIK1 Antibody

Binding Specificity: AA 675-834

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Glutamate receptor ionotropic, kainate 1 protein (675-834AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GRIK1

Target: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Alternative Name: GRIK1

Background:

Background: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.

Aliases: EAA3 antibody, EEA3 antibody, Excitatory amino acid receptor 3 antibody, GLR5 antibody, GluR-5 antibody, GluR5 antibody, GluR6 antibody, GluR7 antibody, Glutamate receptor 5 antibody, Glutamate receptor antibody, Glutamate receptor ionotropic kainate 1 antibody, GRIK1 antibody, GRIK1_HUMAN antibody, Human glutamate receptor GLUR5 antibody, ionotropic kainate 1 antibody, OTTHUMP00000096569 antibody

UniProt: P39086

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity