GRIK1 antibody (AA 271-450)

Catalog No. ABIN3042430

Product Details anti-GRIK1 Antibody

Target: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Binding Specificity: AA 271-450

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIK1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, kainate 1(GRIK1) detection. Tested with WB in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, kainate 1(GRIK1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: glutamate receptor, ionotropic, kainate 1
Protein Name: Glutamate receptor ionotropic, kainate 1

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GRIK1 recombinant protein (Position: R271-I450). Human GRIK1 shares 88% and 94% amino acid (aa) sequences identity with mouse and rat GRIK1, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for GRIK1 is approximately 0.2 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for GRIK1

Target: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Alternative Name: GRIK1 (GRIK1 Products)

Synonyms: GRIK1 antibody, grik1 antibody, fv36b03 antibody, wu:fv36b03 antibody, EAA3 antibody, EEA3 antibody, GLR5 antibody, GLUR5 antibody, GluK1 antibody, A830007B11Rik antibody, D16Ium24 antibody, D16Ium24e antibody, GluK5 antibody, Glur-5 antibody, Glur5 antibody, Glurbeta1 antibody, GluR5 antibody, glutamate ionotropic receptor kainate type subunit 1 antibody, glutamate receptor, ionotropic, kainate 1a antibody, glutamate receptor, ionotropic, kainate 1 antibody, GRIK1 antibody, grik1a antibody, Grik1 antibody

Background: Glutamate receptor, ionotropic, kainate 1, also known as GLUR5, is a protein that in humans is encoded by the GRIK1 gene. It is mapped to 21q21.3. This gene encodes one of the many ionotropic glutamate receptor (GluR) subunits that function as a ligand-gated ion channel. The specific GluR subunit encoded by this gene is of the kainate receptor subtype. Receptor assembly and intracellular trafficking of ionotropic glutamate receptors are regulated by RNA editing and alternative splicing. These receptors mediate excitatory neurotransmission and are critical for normal synaptic function. Exons of this gene are interspersed with exons from the C21or f41 gene, which is transcribed in the same orientation as this gene but does not seem to encode a protein.

Synonyms: EAA3 antibody|EEA3 antibody|Excitatory amino acid receptor 3 antibody|GLR5 antibody|GluR-5 antibody|GluR5 antibody|GluR6 antibody|GluR7 antibody|Glutamate receptor 5 antibody|Glutamate receptor antibody|Glutamate receptor ionotropic kainate 1 antibody|GRIK1 antibody|GRIK1_HUMAN antibody|Human glutamate receptor GLUR5 antibody|ionotropic kainate 1 antibody|OTTHUMP00000096569 antibody

Gene ID: 2897

UniProt: P39086

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity