RIT1 antibody (AA 140-220)

Catalog No. ABIN7216894

This Rabbit Polyclonal antibody specifically detects RIT1 in WB, ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for RIT1 antibody (AA 140-220) (ABIN7216894)

Target: RIT1 (Ras-Like Without CAAX 1 (RIT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RIT1 Antibody

Binding Specificity: AA 140-220

Purpose: Rabbit Anti-Rit1 Polyclonal Antibody

Specificity: Rit1 Polyclonal Antibody detects endogenous levels of Rit1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Rit1 at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RIT1

Target: RIT1 (Ras-Like Without CAAX 1 (RIT1))

Alternative Name: Rit1

Background: RIT1, RIBB, RIT, ROC1, GTP-binding protein Rit1, Ras-like protein expressed in many tissues, Ras-like without CAAX protein 1RIT1 encodes a member of a subfamily of Ras-related GTPases. The GTP-binding protein Rit1 is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants.

Molecular Weight: 25kD

Gene ID: 6016

UniProt: Q92963

Pathways: Neurotrophin Signaling Pathway