NHP2 antibody (AA 1-153)

Catalog No. ABIN7154802

Product Details anti-NHP2 Antibody

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Binding Specificity: AA 1-153

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NHP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human H/ACA ribonucleoprotein complex subunit 2 protein (1-153AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NHP2

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Alternative Name: NHP2 (NHP2 Products)

Synonyms: DKCB2 antibody, NHP2P antibody, NOLA2 antibody, 2410130M07Rik antibody, D11Ertd175e antibody, Nola2 antibody, NHP2 ribonucleoprotein antibody, NHP2 antibody, Nhp2 antibody

Background:

Background: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (\\\"psi\\\") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Aliases: DKCB2 antibody, FLJ20479 antibody, H/ACA ribonucleoprotein complex subunit 2 antibody, NHP2 antibody, NHP2 like protein antibody, NHP2 ribonucleoprotein antibody, NHP2 ribonucleoprotein homolog (yeast) 1 antibody, NHP2 ribonucleoprotein homolog antibody, NHP2, S. cerevisiae, homolog of antibody, NHP2_HUMAN antibody, NHP2P antibody, NOLA2 antibody, Nucleolar protein family A member 2 (H/ACA small nucleolar RNPs) antibody, Nucleolar protein family A member 2 antibody, snoRNP protein NHP2 antibody

UniProt: Q9NX24

Pathways: Telomere Maintenance