NHP2 antibody (AA 21-136)

Catalog No. ABIN7872130

The Rabbit Polyclonal anti-NHP2 antibody (ABIN7872130) specifically detects NHP2 in ELISA, WB, IF, IP and FACS. The antibody is reactive with Human samples.

Quick Overview for NHP2 antibody (AA 21-136) (ABIN7872130)

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NHP2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Product Details anti-NHP2 Antibody

Binding Specificity: AA 21-136

Purpose: NHP2 Antibody / H/ACA ribonucleoprotein complex subunit 2

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E21-Q136) was used as the immunogen for the NHP2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NHP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NHP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NHP2

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Alternative Name: NHP2

Background: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.

UniProt: Q9NX24

Pathways: Telomere Maintenance