HAX1 antibody (AA 2-250)

Catalog No. ABIN7154840

Product Details anti-HAX1 Antibody

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Binding Specificity: AA 2-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human HCLS1-associated protein X-1 protein (2-250AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HAX1

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Alternative Name: HAX1 (HAX1 Products)

Synonyms: HAX1 antibody, hax1 antibody, HCLSBP1 antibody, HS1BP1 antibody, SCN3 antibody, HAX-1 antibody, Hs1bp1 antibody, HSP1BP-1 antibody, SIG-111 antibody, Silg111 antibody, mHAX-1s antibody, HCLS1 associated protein X-1 antibody, HCLS1 associated X-1 antibody, HAX1 antibody, hax1 antibody, Hax1 antibody

Background:

Background: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex (PubMed:26997484). Slows down the rate of inactivation of KCNC3 channels (PubMed:26997484). Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.

Aliases: FLJ17042 antibody, FLJ18492 antibody, FLJ93803 antibody, HAX 1 antibody, HAX-1 antibody, HAX1 antibody, HAX1_HUMAN antibody, Hax1a antibody, HCLS1 and PKD2 associated protein antibody, HCLS1 associated protein antibody, HCLS1 associated protein X 1 antibody, HCLS1-associated protein X-1 antibody, HCLSBP1 antibody, HS 1 associated protein X 1 antibody, HS 1 binding protein antibody, HS1 associating protein X 1 antibody, HS1 binding protein 1 antibody, HS1 binding protein antibody, HS1-associating protein X-1 antibody, HS1-binding protein 1 antibody, HS1BP1 antibody, HSP1BP-1 antibody, OTTHUMP00000034190 antibody, SCN3 antibody

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization