HAX1 antibody (AA 2-250) (FITC)
Quick Overview for HAX1 antibody (AA 2-250) (FITC) (ABIN7154842)
Target
See all HAX1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 2-250
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human HCLS1-associated protein X-1 protein (2-250AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
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Alternative Name
- HAX1
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Background
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Background: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex (PubMed:26997484). Slows down the rate of inactivation of KCNC3 channels (PubMed:26997484). Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.
Aliases: FLJ17042 antibody, FLJ18492 antibody, FLJ93803 antibody, HAX 1 antibody, HAX-1 antibody, HAX1 antibody, HAX1_HUMAN antibody, Hax1a antibody, HCLS1 and PKD2 associated protein antibody, HCLS1 associated protein antibody, HCLS1 associated protein X 1 antibody, HCLS1-associated protein X-1 antibody, HCLSBP1 antibody, HS 1 associated protein X 1 antibody, HS 1 binding protein antibody, HS1 associating protein X 1 antibody, HS1 binding protein 1 antibody, HS1 binding protein antibody, HS1-associating protein X-1 antibody, HS1-binding protein 1 antibody, HS1BP1 antibody, HSP1BP-1 antibody, OTTHUMP00000034190 antibody, SCN3 antibody
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UniProt
- O00165
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Pathways
- Regulation of Actin Filament Polymerization
Target
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