KAT2B antibody (AA 767-832) (HRP)

Catalog No. ABIN7155273

The Rabbit Polyclonal anti-KAT2B antibody has been validated for ELISA. It is suitable to detect KAT2B in samples from Human.

Quick Overview for KAT2B antibody (AA 767-832) (HRP) (ABIN7155273)

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT2B antibody is conjugated to HRP

Application: ELISA

Product Details anti-KAT2B Antibody (HRP)

Binding Specificity: AA 767-832

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Histone acetyltransferase KAT2B protein (767-832AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KAT2B

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Alternative Name: KAT2B

Background:

Background: Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat\'s transactivating activity and may help inducing chromatin remodeling of proviral genes. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers.

Aliases: CAF antibody, CREBBP associated factor antibody, GCN5 antibody, GCN5L antibody, GCN5L1 antibody, Histone acetylase PCAF antibody, Histone acetyltransferase KAT2B antibody, Histone acetyltransferase PCAF antibody, K(lysine) acetyltransferase 2B antibody, KAT2B antibody, KAT2B_HUMAN antibody, Lysine acetyltransferase 2B antibody, P antibody, P/CAF antibody, p300/CBP associated factor antibody, P300/CBP-associated factor antibody, Pcaf antibody

UniProt: Q92831

Pathways: p53 Signaling, Regulation of Carbohydrate Metabolic Process