H2AFZ antibody (AA 1-128)
Quick Overview for H2AFZ antibody (AA 1-128) (ABIN7155385)
Target
See all H2AFZ AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-128
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Histone H2A.Z protein (1-128AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
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Alternative Name
- H2AFZ
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Background
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Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
Aliases: H2A histone family member Z antibody, H2A.z antibody, H2A/z antibody, H2afz antibody, H2AZ antibody, H2AZ_HUMAN antibody, Histone H2A.Z antibody, MGC117173 antibody
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UniProt
- P0C0S5
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Pathways
- Telomere Maintenance
Target
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