Retinoblastoma Binding Protein 4 antibody (AA 246-425)

Catalog No. ABIN7155453

The Rabbit Polyclonal anti-Retinoblastoma Binding Protein 4 antibody has been validated for WB, IHC and ELISA. It is suitable to detect Retinoblastoma Binding Protein 4 in samples from Human.

Quick Overview for Retinoblastoma Binding Protein 4 antibody (AA 246-425) (ABIN7155453)

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Retinoblastoma Binding Protein 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Retinoblastoma Binding Protein 4 Antibody

Binding Specificity: AA 246-425

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Histone-binding protein RBBP4 protein (246-425AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Retinoblastoma Binding Protein 4

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Alternative Name: RBBP4

Background:

Background: Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.

Aliases: CAF I p48 antibody, CAF-1 subunit C antibody, CAF-I 48 kDa subunit antibody, CAF-I p48 antibody, Chromatin assembly factor 1 subunit C antibody, Chromatin assembly factor I p48 subunit antibody, Chromatin assembly factor/CAF 1 p48 subunit antibody, Histone-binding protein RBBP4 antibody, MSI1 protein homolog antibody, Nucleosome-remodeling factor subunit RBAP48 antibody, NURF55 antibody, RB binding protein 4 chromatin remodeling factor antibody, RbAp 48 antibody, RBAP48 antibody, RBBP-4 antibody, RBBP4 antibody, RBBP4_HUMAN antibody, Retinoblastoma binding protein 4 antibody, Retinoblastoma binding protein p48 antibody, Retinoblastoma-binding protein 4 antibody, Retinoblastoma-binding protein p48 antibody

UniProt: Q09028

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus