DOT1L antibody (AA 331-484) (HRP)

Catalog No. ABIN7155533

This Rabbit Polyclonal antibody specifically detects DOT1L in ELISA. It exhibits reactivity toward Human.

Quick Overview for DOT1L antibody (AA 331-484) (HRP) (ABIN7155533)

Target: DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOT1L antibody is conjugated to HRP

Application: ELISA

Product Details anti-DOT1L Antibody (HRP)

Binding Specificity: AA 331-484

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Histone-lysine N-methyltransferase, H3 lysine-79 specific protein (331-484AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DOT1L

Target: DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))

Alternative Name: DOT1L

Background:

Background: Histone methyltransferase. Methylates \'Lys-79\' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.

Aliases: Disrupter of telomere silencing protein 1 antibody, DOT 1 antibody, DOT1 antibody, DOT1 like antibody, DOT1 like histone H3 methyltransferase (S. cerevisiae) antibody, DOT1 like histone H3 methyltransferase antibody, DOT1 like histone H3K79 methyltransferase antibody, DOT1 like protein antibody, DOT1, S. cerevisiae, homolog of antibody, DOT1-like protein antibody, DOT1L antibody, DOT1L_HUMAN antibody, EC 2.1.1.43 antibody, H3 K79 HMTase antibody, H3 lysine-79 specific antibody, H3-K79-HMTase antibody, Histone H3 K79 methyltransferase antibody, Histone H3 methyltransferase antibody, Histone H3 methyltransferase DOT1-like antibody, Histone H3-K79 methyltransferase antibody, Histone lysine N methyltransferase H3 lysine 79 specific antibody, Histone methyltransferase DOT1L antibody, Histone-lysine N-methyltransferase antibody, KIAA1814 antibody, KMT4 antibody, Lysine N methyltransferase 4 antibody, Lysine N-methyltransferase 4 antibody

UniProt: Q8TEK3