MCL-1 antibody (AA 19-244) (Biotin)

Catalog No. ABIN7156220

This Rabbit Polyclonal antibody specifically detects MCL-1 in ELISA. It exhibits reactivity toward Human.

Quick Overview for MCL-1 antibody (AA 19-244) (Biotin) (ABIN7156220)

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCL-1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-MCL-1 Antibody (Biotin)

Binding Specificity: AA 19-244

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Induced myeloid leukemia cell differentiation protein Mcl-1 protein (19-244AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Alternative Name: MCL1

Background:

Background: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Aliases: Bcl 2 related protein EAT/mcl1 antibody, Bcl-2-like protein 3 antibody, Bcl-2-related protein EAT/mcl1 antibody, BCL2 related antibody, Bcl2-L-3 antibody, BCL2L3 antibody, EAT antibody, Induced myeloid leukemia cell differentiation protein Mcl 1 antibody, Induced myeloid leukemia cell differentiation protein Mcl-1 antibody, MCL 1 antibody, MCL1 antibody, MCL1-ES antibody, mcl1/EAT antibody, MCL1_HUMAN antibody, MCL1L antibody, MCL1S antibody, MGC104264 antibody, MGC1839 antibody, Myeloid Cell Leukemia 1 antibody, Myeloid cell leukemia ES antibody, Myeloid cell leukemia sequence 1 antibody, Myeloid cell leukemia sequence 1 BCL2 related antibody, Myeloid cell leukemia sequence 1 isoform 1 antibody, OTTHUMP00000032794 antibody, OTTHUMP00000032795 antibody, TM antibody

UniProt: Q07820

Pathways: MAPK Signaling