IVNS1ABP antibody (AA 401-642) (FITC)
Quick Overview for IVNS1ABP antibody (AA 401-642) (FITC) (ABIN7156225)
Target
See all IVNS1ABP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 401-642
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Influenza virus NS1A-binding protein (401-642AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))
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Alternative Name
- IVNS1ABP
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Target Type
- Influenza Protein
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Background
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Background: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization, Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing, may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
Aliases: IVNS1ABP antibody, ARA3 antibody, FLARA3 antibody, KIAA0850 antibody, KLHL39 antibody, NS1 antibody, NS1BP antibody, HSPC068 antibody, Influenza virus NS1A-binding protein antibody, NS1-BP antibody, NS1-binding protein antibody, Aryl hydrocarbon receptor-associated protein 3 antibody, Kelch-like protein 39 antibody
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UniProt
- Q9Y6Y0
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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