IMPDH2 antibody (AA 5-514) (Biotin)

Catalog No. ABIN7156283

This Rabbit Polyclonal antibody specifically detects IMPDH2 in ELISA. It exhibits reactivity toward Human.

Quick Overview for IMPDH2 antibody (AA 5-514) (Biotin) (ABIN7156283)

Target: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPDH2 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-IMPDH2 Antibody (Biotin)

Binding Specificity: AA 5-514

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Inosine-5\'-monophosphate dehydrogenase 2 protein (5-514AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IMPDH2

Target: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Alternative Name: IMPDH2

Background:

Background: Catalyzes the conversion of inosine 5\'-phosphate (IMP) to xanthosine 5\'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Aliases: IMDH2_HUMAN antibody, IMP (inosine monophosphate) dehydrogenase 2 antibody, IMP dehydrogenase 2 antibody, IMP oxireductase 2 antibody, IMPD 2 antibody, IMPD2 antibody, IMPDH 2 antibody, IMPDH II antibody, IMPDH-II antibody, Impdh2 antibody, Inosine 5' monophosphate dehydrogenase 2 antibody, Inosine 5' phosphate dehydrogenase 2 antibody, Inosine monophosphate dehydrogenase type II antibody, Inosine-5''-monophosphate dehydrogenase 2 antibody

UniProt: P12268

Pathways: Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome