IMPDH2 antibody (AA 215-514)

Catalog No. ABIN7267853

The Rabbit Polyclonal anti-IMPDH2 antibody is suitable to detect IMPDH2 in samples from Human. It has been validated for WB and IHC.

Quick Overview for IMPDH2 antibody (AA 215-514) (ABIN7267853)

Target: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPDH2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IMPDH2 Antibody

Binding Specificity: AA 215-514

Purpose: IMPDH2 Rabbit pAb

Sequence: DDELVAIIAR TDLKKNRDYP LASKDAKKQL LCGAAIGTHE DDKYRLDLLA QAGVDVVVLD SSQGNSIFQI NMIKYIKDKY PNLQVIGGNV VTAAQAKNLI DAGVDALRVG MGSGSICITQ EVLACGRPQA TAVYKVSEYA RRFGVPVIAD GGIQNVGHIA KALALGASTV MMGSLLAATT EAPGEYFFSD GIRLKKYRGM GSLDAMDKHL SSQNRYFSEA DKIKVAQGVS GAVQDKGSIH KFVPYLIAGI QHSCQDIGAK SLTQVRAMMY SGELKFEKRT SSAQVEGGVH SLHSYEKRLF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 215-514 of human IMPDH2 (NP_000875.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IMPDH2

Target: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Alternative Name: IMPDH2

Background: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.,IMPDH2,IMPD2,IMPDH-II,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,IMPDH2

Molecular Weight: 55kDa

Gene ID: 3615

UniProt: P12268

Pathways: Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome