IMPDH2 antibody (AA 215-514)

Catalog No. ABIN7156290

The Rabbit Polyclonal anti-IMPDH2 antibody has been validated for ELISA and IHC. It is suitable to detect IMPDH2 in samples from Human.

Quick Overview for IMPDH2 antibody (AA 215-514) (ABIN7156290)

Target: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPDH2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-IMPDH2 Antibody

Binding Specificity: AA 215-514

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Inosine-5\\\'-monophosphate dehydrogenase 2 protein (215-514AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IMPDH2

Target: IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))

Alternative Name: IMPDH2

Background:

Background: Catalyzes the conversion of inosine 5\\\'-phosphate (IMP) to xanthosine 5\\\'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Aliases: IMDH2_HUMAN antibody, IMP (inosine monophosphate) dehydrogenase 2 antibody, IMP dehydrogenase 2 antibody, IMP oxireductase 2 antibody, IMPD 2 antibody, IMPD2 antibody, IMPDH 2 antibody, IMPDH II antibody, IMPDH-II antibody, Impdh2 antibody, Inosine 5' monophosphate dehydrogenase 2 antibody, Inosine 5' phosphate dehydrogenase 2 antibody, Inosine monophosphate dehydrogenase type II antibody, Inosine-5''-monophosphate dehydrogenase 2 antibody

UniProt: P12268

Pathways: Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome