INTS6 antibody (AA 571-795) (HRP)

Catalog No. ABIN7156420

Product Details anti-INTS6 Antibody (HRP)

Target: INTS6 (Integrator Complex Subunit 6 (INTS6))

Binding Specificity: AA 571-795

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS6 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Integrator complex subunit 6 protein (571-795AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for INTS6

Target: INTS6 (Integrator Complex Subunit 6 (INTS6))

Alternative Name: INTS6 (INTS6 Products)

Synonyms: DBI-1 antibody, DDX26 antibody, DDX26A antibody, DICE1 antibody, HDB antibody, INT6 antibody, Notchl2 antibody, EIF3-P48 antibody, EIF3S6 antibody, eIF3-p46 antibody, 2900075H24Rik antibody, AI480962 antibody, Ddx26 antibody, Notch2l antibody, LRRGT00024 antibody, ints6 antibody, zgc:63527 antibody, INTS6 antibody, ints6-b antibody, Int6-A antibody, dbi-1 antibody, ddx26 antibody, ddx26a antibody, dice1 antibody, hdb antibody, int6 antibody, ints6-a antibody, notchl2 antibody, integrator complex subunit 6 antibody, eukaryotic translation initiation factor 3 subunit E antibody, integrator complex subunit 6 like antibody, integrator complex subunit 6 S homeolog antibody, integrator complex subunit 6 L homeolog antibody, INTS6 antibody, EIF3E antibody, Ints6 antibody, ints6l antibody, ints6 antibody, ints6.S antibody, Tsp_09465 antibody, LOC100164318 antibody, ints6.L antibody

Background:

Background: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3\'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role, an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144).

Aliases: DBI 1 antibody, DBI-1 antibody, DBI1 antibody, DDX26 antibody, DDX26A antibody, DEAD box protein antibody, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26 antibody, Deleted in cancer 1 antibody, DICE1 antibody, DKFZp434B105 antibody, HDB antibody, Int6 antibody, INT6_HUMAN antibody, Integrator complex subunit 6 antibody, INTS 6 antibody, ints6 antibody, Notchl2 antibody, OTTHUMP00000018439 antibody, OTTHUMP00000215034 antibody, OTTHUMP00000215036 antibody, Protein DDX26 antibody, Protein deleted in cancer 1 antibody, RNA helicase HDB antibody

UniProt: Q9UL03