CD11b antibody (AA 46-150)

Catalog No. ABIN7156464

The Rabbit Polyclonal anti-CD11b antibody has been validated for IHC, IF and ELISA. It is suitable to detect CD11b in samples from Human.

Quick Overview for CD11b antibody (AA 46-150) (ABIN7156464)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD11b antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-CD11b Antibody

Binding Specificity: AA 46-150

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Integrin alpha-M protein (46-150AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: ITGAM

Background:

Background: Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Aliases: antigen CD11b (p170) antibody, Antigen CD11b p170 antibody, CD11 antigen like family member B antibody, CD11 antigen-like family member B antibody, CD11b antibody, CD11b/CD18 antibody, CD49d antibody, Cell surface glycoprotein MAC-1 subunit alpha antibody, Complement component 3 receptor 3 subunit antibody, Complement Component Receptor 3 Alpha antibody, Complement receptor type 3 antibody, Complement receptor type 3, alpha subunit antibody, CR 3 alpha chain (CR3A) antibody, CR 3 alpha chain antibody, CR-3 alpha chain antibody, CR3 antibody, CR3A antibody, F730045J24Rik antibody, Integrin Alpha M antibody, Integrin alpha M chain antibody, Integrin alpha-M antibody, Integrin beta 2 alpha subunit antibody, Integrin subunit alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, ITAM_HUMAN antibody, ITGAM antibody, Leukocyte adhesion receptor MO1 antibody, Ly-40 antibody, MAC 1 antibody, Mac-1a antibody, MAC1 antibody, Mac1, alpha subunit antibody, MAC1A antibody, Macrophage antigen alpha polypeptide antibody, MGC117044 antibody, Mo1 antibody, Mo1, alpha subunit antibody, MO1A antibody, Neutrophil adherence receptor alpha M subunit antibody, Neutrophil adherence receptor antibody, SLEB6 antibody

UniProt: P11215

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation