IL-33 antibody (AA 123-276)

Catalog No. ABIN7156895

This Rabbit Polyclonal antibody specifically detects IL-33 in ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for IL-33 antibody (AA 123-276) (ABIN7156895)

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-33 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IL-33 Antibody

Binding Specificity: AA 123-276

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-33 protein (123-276AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL-33

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Alternative Name: IL33

Background:

Background: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an \\\"alarmin\\\", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528).

Aliases: C9orf26 antibody, CHROMOSOME 9 OPEN READING FRAME 26 antibody, DKFZp586H0523 antibody, DVS27 antibody, DVS27 related protein antibody, IL 1F11 antibody, IL 33 antibody, IL-1F11 antibody, IL-33 antibody, IL1F11 antibody, IL33 antibody, IL33_HUMAN antibody, Interleukin 1 family member 11 antibody, Interleukin 33 antibody, INTERLEUKIN 33 NFHEV antibody, Interleukin 33 precursor antibody, Interleukin-1 family member 11 antibody, Interleukin-33 (109-270) antibody, Interleukin33 antibody, NF HEV antibody, NF-HEV antibody, NFEHEV antibody, NFHEV antibody, Nuclear factor for high endothelial venules antibody, Nuclear factor from high endothelial venules antibody, OTTHUMP00000021041 antibody, RP11 575C20.2 antibody

UniProt: O95760

Pathways: Production of Molecular Mediator of Immune Response