IL-6 antibody (AA 30-212)

Catalog No. ABIN7156922

This Rabbit Polyclonal antibody specifically detects IL-6 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for IL-6 antibody (AA 30-212) (ABIN7156922)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-IL-6 Antibody

Binding Specificity: AA 30-212

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-6 protein (30-212AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Alternative Name: IL6

Background:

Background: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.

Aliases: Interleukin BSF 2 antibody, B cell differentiation factor antibody, B cell stimulatory factor 2 antibody, B-cell stimulatory factor 2 antibody, BSF 2 antibody, BSF-2 antibody, BSF2 antibody, CDF antibody, CTL differentiation factor antibody, Cytotoxic T cell differentiation factor antibody, Hepatocyte stimulating factor antibody, Hepatocyte stimulatory factor antibody, HGF antibody, HSF antibody, Hybridoma growth factor antibody, Hybridoma growth factor Interferon beta-2 antibody, Hybridoma plasmacytoma growth factor antibody, IFN-beta-2 antibody, IFNB2 antibody, IL 6 antibody, IL-6 antibody, IL6 antibody, IL6_HUMAN antibody, Interferon beta 2 antibody, Interferon beta-2 antibody, Interleukin 6 antibody, Interleukin 6 (interferon beta 2) antibody, Interleukin BSF 2 antibody, Interleukin-6 antibody

UniProt: P05231

Pathways: TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome