JUP antibody (AA 1-131) (Biotin)

Catalog No. ABIN7157159

This Rabbit Polyclonal antibody specifically detects JUP in ELISA. It exhibits reactivity toward Human.

Quick Overview for JUP antibody (AA 1-131) (Biotin) (ABIN7157159)

Target: JUP (Junction Plakoglobin (JUP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JUP antibody is conjugated to Biotin

Application: ELISA

Product Details anti-JUP Antibody (Biotin)

Binding Specificity: AA 1-131

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Junction plakoglobin protein (1-131AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: JUP

Background:

Background: Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).

Aliases: ARVD 12 antibody, ARVD12 antibody, Catenin (cadherin associated protein), gamma 80 kDa antibody, catenin (cadherin-associated protein) gamma (80kD) antibody, Catenin gamma antibody, CTNNG antibody, Desmoplakin 3 antibody, Desmoplakin III antibody, Desmoplakin-3 antibody, Desmoplakin3 antibody, DesmoplakinIII antibody, DP 3 antibody, DP III antibody, DP3 antibody, DPIII antibody, gamma catenin antibody, Junction plakoglobin antibody, JUP antibody, OTTHUMP00000164732 antibody, OTTHUMP00000164735 antibody, OTTHUMP00000164738 antibody, PDGB antibody, PKGB antibody, PLAK_HUMAN antibody, PLAKOGLOBIN antibody

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location