LBP antibody (AA 304-414)

Catalog No. ABIN7158434

This Rabbit Polyclonal antibody specifically detects LBP in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for LBP antibody (AA 304-414) (ABIN7158434)

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LBP antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-LBP Antibody

Binding Specificity: AA 304-414

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Lipopolysaccharide-binding protein (304-414AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LBP

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Alternative Name: LBP

Background:

Background: Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria (PubMed:7517398, PubMed:24120359). Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:7517398, PubMed:24120359).

Aliases: BPI fold containing family D, member 2 antibody, Bpifd2 antibody, LBP antibody, LBP_HUMAN antibody, LBP1 antibody, Lipopolysaccharide binding protein antibody, Lipopolysaccharide-binding protein antibody, LPS binding protein antibody, Ly88 antibody, MGC22233 antibody, OTTHUMP00000030965 antibody, RP23-407H16.4 antibody

UniProt: P18428

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process