MED17 antibody (AA 411-651) (Biotin)

Catalog No. ABIN7159113

The Rabbit Polyclonal anti-MED17 antibody has been validated for ELISA. It is suitable to detect MED17 in samples from Human.

Quick Overview for MED17 antibody (AA 411-651) (Biotin) (ABIN7159113)

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED17 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-MED17 Antibody (Biotin)

Binding Specificity: AA 411-651

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mediator of RNA polymerase II transcription subunit 17 protein (411-651AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MED17

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Alternative Name: MED17

Background:

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Aliases: 77-KD subunit antibody, Activator recruited cofactor 77 kDa component antibody, Activator-recruited cofactor 77 kDa component antibody, ARC77 antibody, Cofactor required for Sp1 transcriptional activation subunit 6 antibody, cofactor required for Sp1 transcriptional activation, subunit 6, 77 kDa antibody, CRSP complex subunit 6 antibody, CRSP6 antibody, CRSP77 antibody, DRIP80 antibody, med17 antibody, MED17_HUMAN antibody, Mediator complex subunit 17 antibody, Mediator of RNA polymerase II transcription subunit 17 antibody, Mediator of RNA polymerase II transcription subunit 17, S cerevisiae, homolog of antibody, Thyroid hormone receptor-associated protein complex 80 kDa component antibody, Thyroid hormone receptor-associated protein, 80-KD subunit antibody, Transcriptional coactivator CRSP77 antibody, Trap80 antibody, VITAMIN D RECEPTOR-INTERACTING PROTEIN, 80-KD antibody, Vitamin D3 receptor-interacting protein complex 80 kDa component antibody

UniProt: Q9NVC6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha