SPO11 antibody (AA 28-109)

Catalog No. ABIN7159201

The Rabbit Polyclonal anti-SPO11 antibody (ABIN7159201) specifically detects SPO11 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for SPO11 antibody (AA 28-109) (ABIN7159201)

Target: SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPO11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SPO11 Antibody

Binding Specificity: AA 28-109

Purpose: SPO11 Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Meiotic recombination protein SPO11 protein (28-109AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SPO11

Target: SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))

Alternative Name: SPO11

Background:

Background: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.

Aliases: Cancer/testis antigen 35 antibody, CT35 antibody, Meiotic recombination protein SPO 11 antibody, Meiotic recombination protein SPO11 antibody, MGC39953 antibody, SPATA43 antibody, Spermatogenesis associated 43 antibody, SPO 11 antibody, SPO11 antibody, SPO11 meiotic protein covalently bound to DSB antibody, SPO11 meiotic protein covalently bound to DSB homolog antibody, SPO11 meiotic protein covalently bound to DSB like antibody, SPO11_HUMAN antibody, TOPVIA antibody

UniProt: Q9Y5K1