Melanoma gp100 antibody (AA 25-467) (Biotin)

Catalog No. ABIN7159230

The Rabbit Polyclonal anti-Melanoma gp100 antibody has been validated for ELISA. It is suitable to detect Melanoma gp100 in samples from Human.

Quick Overview for Melanoma gp100 antibody (AA 25-467) (Biotin) (ABIN7159230)

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melanoma gp100 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Melanoma gp100 Antibody (Biotin)

Binding Specificity: AA 25-467

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Melanocyte protein PMEL protein (25-467AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Melanoma gp100

Target: Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

Alternative Name: PMEL

Background:

Background: Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.

Aliases: 95 kDa melanocyte specific secreted glycoprotein antibody, 95 kDa melanocyte-specific secreted glycoprotein antibody, D12S53E antibody, gp100 antibody, M-beta antibody, ME20 antibody, ME20 M/ME20 S antibody, ME20-M antibody, ME20-S antibody, ME20M antibody, ME20M/ME20S antibody, ME20S antibody, Melanocyte lineage specific antigen GP100 antibody, Melanocyte protein mel 17 antibody, Melanocyte protein Pmel 17 antibody, Melanocyte protein Pmel 17 precursor antibody, Melanocytes lineage-specific antigen GP100 antibody, Melanoma associated ME20 antigen antibody, Melanoma gp100 antibody, Melanoma-associated ME20 antigen antibody, Melanosomal matrix protein 17 antibody, Melanosomal matrix protein17 antibody, P1 antibody, p100 antibody, p26 antibody, PMEL 17 antibody, PMEL antibody, PMEL_HUMAN antibody, PMEL17 antibody, Premelanosome protein antibody, Secreted melanoma-associated ME20 antigen antibody, SI antibody, SIL antibody, SILV antibody, Silver (mouse homolog) like antibody, Silver homolog antibody, Silver locus protein homolog antibody, Silver, mouse, homolog of antibody

UniProt: P40967