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MSH6 antibody

MSH6 Reactivity: Human IHC, ELISA Host: Mouse Monoclonal 2C12F3 unconjugated
Catalog No. ABIN7160272
  • Target See all MSH6 Antibodies
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Reactivity
    • 76
    • 35
    • 29
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 58
    • 15
    • 3
    Mouse
    Clonality
    • 46
    • 30
    Monoclonal
    Conjugate
    • 44
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MSH6 antibody is un-conjugated
    Application
    • 52
    • 26
    • 23
    • 19
    • 14
    • 13
    • 11
    • 8
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    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human
    Purification
    Protein G purified
    Immunogen
    Recombinant Human MSH6 Protein
    Clone
    2C12F3
    Isotype
    IgG
    Top Product
    Discover our top product MSH6 Primary Antibody
  • Application Notes
    Recommended dilution:IHC:1:50-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Alternative Name
    MSH6 (MSH6 Products)
    Synonyms
    GTBP antibody, GTMBP antibody, HNPCC5 antibody, HSAP antibody, p160 antibody, cb326 antibody, wu:fb36c12 antibody, LOC100227810 antibody, AU044881 antibody, AW550279 antibody, Gtmbp antibody, mutS homolog 6 antibody, mutS homolog 6 (E. coli) antibody, DNA mismatch repair protein antibody, MSH6 antibody, msh6 antibody, Msh6 antibody
    Background

    Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa,called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have beendescribed.

    Aliases: MutS Homolog 6,GTBP,HSAP2,DNA Mismatch Repair Protein Msh6,G/T Mismatch-Binding Protein

    UniProt
    P52701
    Pathways
    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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