MEF2A antibody (AA 72-226) (Biotin)

Catalog No. ABIN7160501

This Rabbit Polyclonal antibody specifically detects MEF2A in ELISA. It exhibits reactivity toward Human.

Quick Overview for MEF2A antibody (AA 72-226) (Biotin) (ABIN7160501)

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2A antibody is conjugated to Biotin

Application: ELISA

Product Details anti-MEF2A Antibody (Biotin)

Binding Specificity: AA 72-226

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Myocyte-specific enhancer factor 2A protein (72-226AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MEF2A

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Alternative Name: MEF2A

Background:

Background: Transcriptional activator which binds specifically to the MEF2 element, 5\'-YTA[AT](4)TAR-3\', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

Aliases: ADCAD1 antibody, MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) antibody, MEF2 antibody, MEF2A antibody, MEF2A_HUMAN antibody, Myocyte enhancer factor 2A antibody, Myocyte-specific enhancer factor 2A antibody, RSRFC4 antibody, RSRFC9 antibody, Serum response factor like protein 1 antibody, Serum response factor-like protein 1 antibody

UniProt: Q02078

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades