NEDD8 antibody (AA 1-81)

Catalog No. ABIN7161130

The Rabbit Polyclonal anti-NEDD8 antibody (ABIN7161130) specifically detects NEDD8 in WB, IHC, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for NEDD8 antibody (AA 1-81) (ABIN7161130)

Target: NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEDD8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-NEDD8 Antibody

Binding Specificity: AA 1-81

Purpose: NEDD8 Antibody

Cross-Reactivity: Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human NEDD8 protein (1-81AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NEDD8

Target: NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))

Alternative Name: NEDD8

Background:

Background: Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.

Aliases: FLJ43224 antibody, MGC104393 antibody, MGC125896 antibody, MGC125897 antibody, NED8 antibody, NEDD 8 antibody, NEDD-8 antibody, Nedd8 antibody, NEDD8_HUMAN antibody, Neddylin antibody, Neural precursor cell expressed developmentally down regulated 8 antibody, Neural precursor cell expressed developmentally down regulated gene 8 antibody, Neural precursor cell expressed developmentally down-regulated protein 8 antibody, Rub1 antibody, Ubiquitin like protein Nedd 8 antibody, Ubiquitin like protein Nedd8 antibody, Ubiquitin-like protein Nedd8 antibody

UniProt: Q15843

Pathways: Ubiquitin Proteasome Pathway